Preeclampsia serum-induced collagen I expression and intracellular calcium levels in arterial smooth muscle cells are mediated by the PLC-γ1 pathway

In women with preeclampsia (PE), endothelial cell (EC) dysfunction can lead to altered secretion of paracrine factors that induce peripheral vasoconstriction and proteinuria. This study examined the hypothesis that PE sera may directly or indirectly, through human umbilical vein ECs (HUVECs), stimul...

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Detalhes bibliográficos
Main Authors: Jiang, Rongzhen, Teng, Yincheng, Huang, Yajuan, Gu, Jinghong, Ma, Li, Li, Ming, Zhou, Yuedi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183944/
https://ncbi.nlm.nih.gov/pubmed/25257609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.59
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