Preeclampsia serum-induced collagen I expression and intracellular calcium levels in arterial smooth muscle cells are mediated by the PLC-γ1 pathway

In women with preeclampsia (PE), endothelial cell (EC) dysfunction can lead to altered secretion of paracrine factors that induce peripheral vasoconstriction and proteinuria. This study examined the hypothesis that PE sera may directly or indirectly, through human umbilical vein ECs (HUVECs), stimul...

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Autors principals: Jiang, Rongzhen, Teng, Yincheng, Huang, Yajuan, Gu, Jinghong, Ma, Li, Li, Ming, Zhou, Yuedi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183944/
https://ncbi.nlm.nih.gov/pubmed/25257609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.59
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