Ca(2+)-mediated Mitochondrial Reactive Oxygen Species Metabolism Augments Wnt/β-Catenin Pathway Activation to Facilitate Cell Differentiation

Emerging evidence suggests that reactive oxygen species (ROS) can stimulate the Wnt/β-catenin pathway in a number of cellular processes. However, potential sources of endogenous ROS have not been thoroughly explored. Here, we show that growth factor depletion in human neural progenitor cells induces...

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Detalhes bibliográficos
Main Authors: Rharass, Tareck, Lemcke, Heiko, Lantow, Margareta, Kuznetsov, Sergei A., Weiss, Dieter G., Panáková, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183826/
https://ncbi.nlm.nih.gov/pubmed/25124032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.573519
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