Pharmacological Profile of Brain-derived Neurotrophic Factor (BDNF) Splice Variant Translation Using a Novel Drug Screening Assay: A “QUANTITATIVE CODE”

The neurotrophin brain-derived neurotrophic factor (BDNF) is a key regulator of neuronal development and plasticity. BDNF is a major pharmaceutical target in neurodevelopmental and psychiatric disorders. However, pharmacological modulation of this neurotrophin is challenging because BDNF is generate...

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Autors principals: Vaghi, Valentina, Polacchini, Alessio, Baj, Gabriele, Pinheiro, Vera L. M., Vicario, Annalisa, Tongiorgi, Enrico
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Neurobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183807/
https://ncbi.nlm.nih.gov/pubmed/25074925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.586719
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