Inflammatory Monocytes Determine Endothelial Nitric-oxide Synthase Uncoupling and Nitro-oxidative Stress Induced by Angiotensin II

Endothelial nitric-oxide synthase (eNOS) uncoupling and increased inducible NOS (iNOS) activity amplify vascular oxidative stress. The role of inflammatory myelomonocytic cells as mediators of these processes and their impact on tetrahydrobiopterin availability and function have not yet been defined...

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Detalhes bibliográficos
Main Authors: Kossmann, Sabine, Hu, Hanhan, Steven, Sebastian, Schönfelder, Tanja, Fraccarollo, Daniela, Mikhed, Yuliya, Brähler, Melanie, Knorr, Maike, Brandt, Moritz, Karbach, Susanne H., Becker, Christian, Oelze, Matthias, Bauersachs, Johann, Widder, Julian, Münzel, Thomas, Daiber, Andreas, Wenzel, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183794/
https://ncbi.nlm.nih.gov/pubmed/25143378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.604231
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