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Heat Shock Protein 70.1 (Hsp70.1) Affects Neuronal Cell Fate by Regulating Lysosomal Acid Sphingomyelinase

The inducible expression of heat shock protein 70.1 (Hsp70.1) plays cytoprotective roles in its molecular chaperone function. Binding of Hsp70 to an endolysosomal phospholipid, bis(monoacylglycero)phosphate (BMP), has been recently shown to stabilize lysosomal membranes by enhancing acid sphingomyel...

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Autori principali: Zhu, Hong, Yoshimoto, Tanihiro, Yamashima, Tetsumori
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183783/
https://ncbi.nlm.nih.gov/pubmed/25074941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.560334
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