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Heat Shock Protein 70.1 (Hsp70.1) Affects Neuronal Cell Fate by Regulating Lysosomal Acid Sphingomyelinase

The inducible expression of heat shock protein 70.1 (Hsp70.1) plays cytoprotective roles in its molecular chaperone function. Binding of Hsp70 to an endolysosomal phospholipid, bis(monoacylglycero)phosphate (BMP), has been recently shown to stabilize lysosomal membranes by enhancing acid sphingomyel...

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Detalhes bibliográficos
Main Authors: Zhu, Hong, Yoshimoto, Tanihiro, Yamashima, Tetsumori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183783/
https://ncbi.nlm.nih.gov/pubmed/25074941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.560334
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