Crystal Structure of the Ubiquitin-like Domain-CUT Repeat-like Tandem of Special AT-rich Sequence Binding Protein 1 (SATB1) Reveals a Coordinating DNA-binding Mechanism

SATB1 is essential for T-cell development and growth and metastasis of multitype tumors and acts as a global chromatin organizer and gene expression regulator. The DNA binding ability of SATB1 plays vital roles in its various biological functions. We report the crystal structure of the N-terminal mo...

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Detalhes bibliográficos
Main Authors: Wang, Zheng, Yang, Xue, Guo, Shuang, Yang, Yin, Su, Xun-Cheng, Shen, Yuequan, Long, Jiafu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183778/
https://ncbi.nlm.nih.gov/pubmed/25124042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.562314
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