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A Short DNA Sequence Confers Strong Bleomycin Binding to Hairpin DNAs

[Image: see text] Bleomycins A(5) and B(2) were used to study the structural features in hairpin DNAs conducive to strong BLM–DNA interaction. Two members of a 10-hairpin DNA library previously found to bind most tightly to these BLMs were subsequently noted to share the sequence 5′-ACGC (complement...

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Detalhes bibliográficos
Main Authors: Tang, Chenhong, Paul, Ananya, Alam, Mohammad P., Roy, Basab, Wilson, W. David, Hecht, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183661/
https://ncbi.nlm.nih.gov/pubmed/25188011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja505733u
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