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Characterization of Bleomycin-Mediated Cleavage of a Hairpin DNA Library

A study of BLM A(5) was conducted using a previously isolated library of hairpin DNAs found to bind strongly to metal free BLM. The ability of Fe(II)•BLM to effect cleavage on both the 3' and 5'-arms of the hairpin DNAs was characterized. The strongly bound DNAs were found to be efficient...

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Detalhes bibliográficos
Main Authors: Segerman, Zachary J., Roy, Basab, Hecht, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859804/
https://ncbi.nlm.nih.gov/pubmed/23834496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400779r
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