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Facilitated Assignment of Large Protein NMR Signals with Covariance Sequential Spectra Using Spectral Derivatives

[Image: see text] Nuclear magnetic resonance (NMR) studies of larger proteins are hampered by difficulties in assigning NMR resonances. Human intervention is typically required to identify NMR signals in 3D spectra, and subsequent procedures depend on the accuracy of this so-called peak picking. We...

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Autors principals: Harden, Bradley J., Nichols, Scott R., Frueh, Dominique P.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183633/
https://ncbi.nlm.nih.gov/pubmed/25226241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5058407
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