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Facilitated Assignment of Large Protein NMR Signals with Covariance Sequential Spectra Using Spectral Derivatives

[Image: see text] Nuclear magnetic resonance (NMR) studies of larger proteins are hampered by difficulties in assigning NMR resonances. Human intervention is typically required to identify NMR signals in 3D spectra, and subsequent procedures depend on the accuracy of this so-called peak picking. We...

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Bibliographische Detailangaben
Hauptverfasser: Harden, Bradley J., Nichols, Scott R., Frueh, Dominique P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183633/
https://ncbi.nlm.nih.gov/pubmed/25226241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja5058407
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