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Exosomes from Hepatitis C Infected Patients Transmit HCV Infection and Contain Replication Competent Viral RNA in Complex with Ago2-miR122-HSP90

Antibodies targeting receptor-mediated entry of HCV into hepatocytes confer limited therapeutic benefits. Evidence suggests that exosomes can transfer genetic materials between cells; however, their role in HCV infection remains obscure. Here, we show that exosomes isolated from sera of chronic HCV...

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Detalhes bibliográficos
Main Authors: Bukong, Terence N., Momen-Heravi, Fatemeh, Kodys, Karen, Bala, Shashi, Szabo, Gyongyi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183590/
https://ncbi.nlm.nih.gov/pubmed/25275643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004424
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