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Alcohol Facilitates HCV RNA Replication Via Up-Regulation of miR-122 Expression and Inhibition of Cyclin G1 in Human Hepatoma Cells

BACKGROUND: Clinical studies demonstrate synergistic liver damage by alcohol and hepatitis C virus (HCV); however, the mechanisms by which alcohol promotes HCV infection remain obscure. The liver-specific microRNA-122 (miR-122) regulates HCV replication and expression of host genes, including Cyclin...

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Dettagli Bibliografici
Autori principali: Hou, Wei, Bukong, Terence N., Kodys, Karen, Szabo, Gyongyi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171687/
https://ncbi.nlm.nih.gov/pubmed/23126531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12005
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