Cyclophilin A Associates with Enterovirus-71 Virus Capsid and Plays an Essential Role in Viral Infection as an Uncoating Regulator

Viruses utilize host factors for their efficient proliferation. By evaluating the inhibitory effects of compounds in our library, we identified inhibitors of cyclophilin A (CypA), a known immunosuppressor with peptidyl-prolyl cis-trans isomerase activity, can significantly attenuate EV71 proliferati...

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Bibliografiske detaljer
Main Authors: Qing, Jie, Wang, Yaxin, Sun, Yuna, Huang, Jiaoyan, Yan, Wenzhong, Wang, Jinglan, Su, Dan, Ni, Cheng, Li, Jian, Rao, Zihe, Liu, Lei, Lou, Zhiyong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183573/
https://ncbi.nlm.nih.gov/pubmed/25275585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004422
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