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Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity
DNA double-strand breaks (DSBs) are perhaps the most toxic of all DNA lesions, with defects in the DNA damage response to DSBs being associated with various human diseases. Although it is known that DSB repair pathways are tightly regulated by ubiquitylation, we do not yet have a comprehensive under...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183562/ https://ncbi.nlm.nih.gov/pubmed/25194926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3028 |
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