Trainable High Resolution Melt Curve Machine Learning Classifier for Large-Scale Reliable Genotyping of Sequence Variants

High resolution melt (HRM) is gaining considerable popularity as a simple and robust method for genotyping sequence variants. However, accurate genotyping of an unknown sample for which a large number of possible variants may exist will require an automated HRM curve identification method capable of...

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Detalhes bibliográficos
Main Authors: Athamanolap, Pornpat, Parekh, Vishwa, Fraley, Stephanie I., Agarwal, Vatsal, Shin, Dong J., Jacobs, Michael A., Wang, Tza-Huei, Yang, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183555/
https://ncbi.nlm.nih.gov/pubmed/25275518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109094
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