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Brugia malayi Microfilariae Induce a Regulatory Monocyte/Macrophage Phenotype That Suppresses Innate and Adaptive Immune Responses

BACKGROUND: Monocytes and macrophages contribute to the dysfunction of immune responses in human filariasis. During patent infection monocytes encounter microfilariae in the blood, an event that occurs in asymptomatically infected filariasis patients that are immunologically hyporeactive. AIM: To de...

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Main Authors: O'Regan, Noëlle Louise, Steinfelder, Svenja, Venugopal, Gopinath, Rao, Gopala B., Lucius, Richard, Srikantam, Aparna, Hartmann, Susanne
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183501/
https://ncbi.nlm.nih.gov/pubmed/25275395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003206
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