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Brugia malayi Microfilariae Induce a Regulatory Monocyte/Macrophage Phenotype That Suppresses Innate and Adaptive Immune Responses

BACKGROUND: Monocytes and macrophages contribute to the dysfunction of immune responses in human filariasis. During patent infection monocytes encounter microfilariae in the blood, an event that occurs in asymptomatically infected filariasis patients that are immunologically hyporeactive. AIM: To de...

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Detalhes bibliográficos
Main Authors: O'Regan, Noëlle Louise, Steinfelder, Svenja, Venugopal, Gopinath, Rao, Gopala B., Lucius, Richard, Srikantam, Aparna, Hartmann, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183501/
https://ncbi.nlm.nih.gov/pubmed/25275395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003206
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