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Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification

Physical stimuli can act in either a synergistic or antagonistic manner to regulate cell fate decisions, but it is less clear whether insoluble signals alone can direct human pluripotent stem (hPS) cell differentiation into specialized cell types. We previously reported that stiff materials promote...

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Bibliografski detalji
Glavni autori: Musah, Samira, Wrighton, Paul J., Zaltsman, Yefim, Zhong, Xiaofen, Zorn, Stefan, Parlato, Matthew B., Hsiao, Cheston, Palecek, Sean P., Chang, Qiang, Murphy, William L., Kiessling, Laura L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183276/
https://ncbi.nlm.nih.gov/pubmed/25201954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415330111
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