Substratum-induced differentiation of human pluripotent stem cells reveals the coactivator YAP is a potent regulator of neuronal specification

Physical stimuli can act in either a synergistic or antagonistic manner to regulate cell fate decisions, but it is less clear whether insoluble signals alone can direct human pluripotent stem (hPS) cell differentiation into specialized cell types. We previously reported that stiff materials promote...

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Detalhes bibliográficos
Main Authors: Musah, Samira, Wrighton, Paul J., Zaltsman, Yefim, Zhong, Xiaofen, Zorn, Stefan, Parlato, Matthew B., Hsiao, Cheston, Palecek, Sean P., Chang, Qiang, Murphy, William L., Kiessling, Laura L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183276/
https://ncbi.nlm.nih.gov/pubmed/25201954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415330111
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