Molecular Profiling of the Invasive Tumor Microenvironment in a 3-Dimensional Model of Colorectal Cancer Cells and Ex vivo Fibroblasts

Invading colorectal cancer (CRC) cells have acquired the capacity to break free from their sister cells, infiltrate the stroma, and remodel the extracellular matrix (ECM). Characterizing the biology of this phenotypically distinct group of cells could substantially improve our understanding of early...

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Detalhes bibliográficos
Main Authors: Bullock, Marc D., Mellone, Max, Pickard, Karen M., Sayan, Abdulkadir Emre, Mitter, Richard, Primrose, John N., Packham, Graham K., Thomas, Gareth, Mirnezami, Alexander H.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183106/
https://ncbi.nlm.nih.gov/pubmed/24836208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51475
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