Molecular Profiling of the Invasive Tumor Microenvironment in a 3-Dimensional Model of Colorectal Cancer Cells and Ex vivo Fibroblasts

Invading colorectal cancer (CRC) cells have acquired the capacity to break free from their sister cells, infiltrate the stroma, and remodel the extracellular matrix (ECM). Characterizing the biology of this phenotypically distinct group of cells could substantially improve our understanding of early...

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Autori principali: Bullock, Marc D., Mellone, Max, Pickard, Karen M., Sayan, Abdulkadir Emre, Mitter, Richard, Primrose, John N., Packham, Graham K., Thomas, Gareth, Mirnezami, Alexander H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2014
Soggetti:
Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183106/
https://ncbi.nlm.nih.gov/pubmed/24836208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51475
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