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Caveolin-1 Increases Proinflammatory Chemoattractants and Blood–Retinal Barrier Breakdown but Decreases Leukocyte Recruitment in Inflammation

PURPOSE. Caveolin-1 (Cav-1), the signature protein of caveolae, modulates inflammatory responses, and innate immunity. However, Cav-1′s role in retinal inflammation has not been rigorously tested. In this study, we examined the effect of Cav-1 ablation on the sensitivity of the retina to inflammatio...

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Detalhes bibliográficos
Main Authors: Li, Xiaoman, Gu, Xiaowu, Boyce, Timothy M., Zheng, Min, Reagan, Alaina M., Qi, Hui, Mandal, Nawajes, Cohen, Alex W., Callegan, Michelle C., Carr, Daniel J. J., Elliott, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183075/
https://ncbi.nlm.nih.gov/pubmed/25159208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14613
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