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Loss of Caveolin-1 Causes Blood–Retinal Barrier Breakdown, Venous Enlargement, and Mural Cell Alteration

Blood–retinal barrier (BRB) breakdown and related vascular changes are implicated in several ocular diseases. The molecules and mechanisms regulating BRB integrity and pathophysiology are not fully elucidated. Caveolin-1 (Cav-1) ablation results in loss of caveolae and microvascular pathologies, but...

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Detalhes bibliográficos
Main Authors: Gu, Xiaowu, Fliesler, Steven J., Zhao, You-Yang, Stallcup, William B., Cohen, Alex W., Elliott, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906491/
https://ncbi.nlm.nih.gov/pubmed/24326256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.10.022
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