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Lessons learned from vivo-morpholinos: How to avoid vivo-morpholino toxicity

Vivo-morpholinos are a promising tool for gene silencing. These oligonucleotide analogs transiently silence genes by blocking either translation or pre-mRNA splicing. Little to no toxicity has been reported for vivo-morpholino treatment. However, in a recent study conducted in our lab, treatment of...

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Autors principals: Ferguson, David P., Dangott, Lawrence J., Lightfoot, J. Timothy
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182913/
https://ncbi.nlm.nih.gov/pubmed/24806225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/000114167
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