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Lessons learned from vivo-morpholinos: How to avoid vivo-morpholino toxicity
Vivo-morpholinos are a promising tool for gene silencing. These oligonucleotide analogs transiently silence genes by blocking either translation or pre-mRNA splicing. Little to no toxicity has been reported for vivo-morpholino treatment. However, in a recent study conducted in our lab, treatment of...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4182913/ https://ncbi.nlm.nih.gov/pubmed/24806225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2144/000114167 |
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