Augmented β-Cell Function and Mass in Glucocorticoid-Treated Rodents Are Associated with Increased Islet Ir-β/AKT/mTOR and Decreased AMPK/ACC and AS160 Signaling

Glucocorticoid (GC) therapies may adversely cause insulin resistance (IR) that lead to a compensatory hyperinsulinemia due to insulin hypersecretion. The increased β-cell function is associated with increased insulin signaling that has the protein kinase B (AKT) substrate with 160 kDa (AS160) as an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Protzek, André O. P., Costa-Júnior, José M., Rezende, Luiz F., Santos, Gustavo J., Araújo, Tiago Gomes, Vettorazzi, Jean F., Ortis, Fernanda, Carneiro, Everardo M., Rafacho, Alex, Boschero, Antonio C.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182854/
https://ncbi.nlm.nih.gov/pubmed/25313308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/983453
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados