Glucagon regulates ACC activity in adipocytes through the CAMKKβ/AMPK pathway

Glucagon is important for regulating lipid metabolism in part through its inhibition of fatty acid synthesis in adipocytes. Acetyl-CoA carboxylase 1 (ACC1) is the rate-limiting enzyme for fatty acid synthesis. Glucagon has been proposed to activate cAMP-dependent protein kinase A (PKA), which phosph...

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Detalhes bibliográficos
Main Authors: Peng, I-Chen, Chen, Zhen, Sun, Wei, Li, Ying-Shiuan, Marin, Traci LaNai, Hsu, Pang-Hung, Su, Mei-I, Cui, Xiaopei, Pan, Songqin, Lytle, Christian Y., Johnson, David A., Blaeser, Frank, Chatila, Talal, Shyy, John Y-J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378158/
https://ncbi.nlm.nih.gov/pubmed/22454291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00504.2011
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