(18)FDG, [(18)F]FLT, [(18)F]FAZA, and (11)C-Methionine Are Suitable Tracers for the Diagnosis and In Vivo Follow-Up of the Efficacy of Chemotherapy by miniPET in Both Multidrug Resistant and Sensitive Human Gynecologic Tumor Xenografts

Expression of multidrug pumps including P-glycoprotein (MDR1, ABCB1) in the plasma membrane of tumor cells often results in decreased intracellular accumulation of anticancer drugs causing serious impediment to successful chemotherapy. It has been shown earlier that combined treatment with UIC2 anti...

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Hauptverfasser: Trencsényi, György, Márián, Teréz, Lajtos, Imre, Krasznai, Zoltán, Balkay, László, Emri, Miklós, Mikecz, Pál, Goda, Katalin, Szalóki, Gábor, Juhász, István, Németh, Enikő, Miklovicz, Tünde, Szabó, Gábor, Krasznai, Zoárd T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182689/
https://ncbi.nlm.nih.gov/pubmed/25309926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/787365
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