ZFC3H1, a Zinc Finger Protein, Modulates IL-8 Transcription by Binding with Celastramycin A, a Potential Immune Suppressor

Celastramycin A, a small molecule that inhibits the production of antibacterial peptides in an ex vivo culture system of Drosophila, suppresses the TNFα-mediated induction of IL-8 in mammalian cells. To understand its molecular mechanism, we examined Celastramycin A binding proteins and investigated...

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Main Authors: Tomita, Takeshi, Ieguchi, Katsuaki, Coin, Fredric, Kato, Yasuhiro, Kikuchi, Haruhisa, Oshima, Yoshiteru, Kurata, Shoichiro, Maru, Yoshiro
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182580/
https://ncbi.nlm.nih.gov/pubmed/25268596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108957
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