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Identification of Essential Proteins Based on Ranking Edge-Weights in Protein-Protein Interaction Networks
Essential proteins are those that are indispensable to cellular survival and development. Existing methods for essential protein identification generally rely on knock-out experiments and/or the relative density of their interactions (edges) with other proteins in a Protein-Protein Interaction (PPI)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4182551/ https://ncbi.nlm.nih.gov/pubmed/25268881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108716 |
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