Combining MK626, a Novel DPP-4 Inhibitor, and Low-Dose Monoclonal CD3 Antibody for Stable Remission of New-Onset Diabetes in Mice

Combining immune intervention with therapies that directly influence the functional state of the β-cells is an interesting strategy in type 1 diabetes cure. Dipeptidyl peptidase-4 (DPP-4) inhibitors elevate circulating levels of active incretins, which have been reported to enhance insulin secretion...

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Detalhes bibliográficos
Main Authors: Ding, Lei, Gysemans, Conny A., Stangé, Geert, Heremans, Yves, Yuchi, Yixing, Takiishi, Tatiana, Korf, Hannelie, Chintinne, Marie, Carr, Richard D., Heimberg, Harry, Pipeleers, Daniel, Mathieu, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182446/
https://ncbi.nlm.nih.gov/pubmed/25268801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107935
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