In TFIIH, XPD Helicase Is Exclusively Devoted to DNA Repair

The eukaryotic XPD helicase is an essential subunit of TFIIH involved in both transcription and nucleotide excision repair (NER). Mutations in human XPD are associated with several inherited diseases such as xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy. We performed a comparativ...

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Detalhes bibliográficos
Main Authors: Kuper, Jochen, Braun, Cathy, Elias, Agnes, Michels, Gudrun, Sauer, Florian, Schmitt, Dominik R., Poterszman, Arnaud, Egly, Jean-Marc, Kisker, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4182028/
https://ncbi.nlm.nih.gov/pubmed/25268380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001954
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