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In Vivo Protection against Strychnine Toxicity in Mice by the Glycine Receptor Agonist Ivermectin
The inhibitory glycine receptor, a ligand-gated ion channel that mediates fast synaptic inhibition in mammalian spinal cord and brainstem, is potently and selectively inhibited by the alkaloid strychnine. The anthelminthic and anticonvulsant ivermectin is a strychnine-independent agonist of spinal g...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi Publishing Corporation
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4181905/ https://ncbi.nlm.nih.gov/pubmed/25317421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/640790 |
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