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Tumor heterogeneity and resistance to EGFR-targeted therapy in advanced nonsmall cell lung cancer: challenges and perspectives

Lung cancer, mostly nonsmall cell lung cancer, continues to be the leading cause of cancer-related death worldwide. With the development of tyrosine kinase inhibitors that selectively target lung cancer-related epidermal growth factor receptor mutations, management of advanced nonsmall cell lung can...

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Bibliographic Details
Main Authors: Cheng, Xinghua, Chen, Haiquan
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181629/
https://ncbi.nlm.nih.gov/pubmed/25285017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S66502
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