Differential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells

Centrosome amplification (CA) amongst particular breast cancer subtypes (Her2+ subtype) is associated with genomic instability and aggressive tumor phenotypes. However, changes in signaling pathways associated with centrosome biology have not been fully explored in subtype specific models. Novel cen...

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Autores principales: Lee, Mi-Young, Marina, Mihaela, King, Jamie L, Saavedra, Harold I
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181616/
https://ncbi.nlm.nih.gov/pubmed/25278993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-9-3
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