Positive feedback regulation of agonist-stimulated endothelial Ca(2+) dynamics by K(Ca)3.1 channels in mouse mesenteric arteries

OBJECTIVE: Intermediate and small conductance K(Ca) channels IK1 (K(Ca)3.1) and SK3 (K(Ca)2.3) are primary targets of endothelial Ca(2+) signals in the arterial vasculature and their ablation results in increased arterial tone and hypertension. Activation of IK1 channels by local Ca(2+) transients f...

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Bibliographic Details
Main Authors:	Qian, Xun, Francis, Michael, Köhler, Ralf, Solodushko, Viktoriya, Lin, Mike, Taylor, Mark S.
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4181598/ https://ncbi.nlm.nih.gov/pubmed/24177326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302506
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Positive feedback regulation of agonist-stimulated endothelial Ca(2+) dynamics by K(Ca)3.1 channels in mouse mesenteric arteries

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