Clinical validation of IFNγ/IL-10 and IFNγ/IL-2 FluoroSpot assays for the detection of Tr1 T cells and influenza vaccine monitoring in humans

The type of T cell polarization and simultaneous production of multiple cytokines have been correlated with vaccine efficacy. ELISpot is a T cell detection technique optimized for the measurement of a secreted cytokine at the single cell level. The FluoroSpot assay differs from ELISpot by the use of...

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Main Authors: Chauvat, Anne, Benhamouda, Nadine, Gey, Alain, Lemoine, Francois M, Paulie, Staffan, Carrat, Fabrice, Gougeon, Marie-Lise, Rozenberg, Flore, Krivine, Anne, Cherai, Mustapha, Lehmann, Paul V, Quintin-Colonna, Françoise, Launay, Odile, Tartour, Eric
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4181035/
https://ncbi.nlm.nih.gov/pubmed/24084262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.26593
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