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Regulated assembly and disassembly of the yeast telomerase quaternary complex

The enzyme telomerase, which elongates chromosome termini, is a critical factor in determining long-term cellular proliferation and tissue renewal. Hence, even small differences in telomerase levels can have substantial consequences for human health. In budding yeast, telomerase consists of the cata...

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Bibliographic Details
Main Authors: Tucey, Timothy M., Lundblad, Victoria
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180971/
https://ncbi.nlm.nih.gov/pubmed/25240060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.246256.114
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