TGF-β isoforms induce EMT independent migration of ovarian cancer cells

BACKGROUND: Transforming growth factor beta (TGF-β) plays major roles in tumorigenesis by regulating cell growth, epithelial-to-mesenchymal transition (EMT), migration/invasion and metastasis. The epithelial markers E-cadherin, claudin-3 and claudin-4, commonly decreased in human adenocarcinomas are...

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Bibliografiske detaljer
Main Authors: Gao, Jingfang, Zhu, Yihong, Nilsson, Mikael, Sundfeldt, Karin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Primary Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180856/
https://ncbi.nlm.nih.gov/pubmed/25278811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0072-1
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