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Whole-genome haplotype reconstruction using proximity-ligation and shotgun sequencing

Rapid advances in high-throughput sequencing facilitate variant discovery and genotyping, but linking variants into a single haplotype remains challenging. Here we demonstrate HaploSeq, an approach for assembling chromosome-scale haplotypes by exploiting the existence of ‘chromosome territories’. We...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Selvaraj, Siddarth, Dixon, Jesse R, Bansal, Vikas, Ren, Bing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180835/
https://ncbi.nlm.nih.gov/pubmed/24185094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2728
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