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Heritable, population-wide damage to cells as the driving force of neoplastic transformation.

Prolonged incubation of NIH 3T3 cells under the growth constraint of confluence results in the death of some cells in a manner suggestive of apoptosis. Successive rounds of prolonged incubation at confluence of the surviving cells produce increasing neoplastic transformation in the form of increment...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rubin, H, Yao, A, Chow, M
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41803/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7761410/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.11.4843
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