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A critical test of the role of population density in producing transformation.

Cells of the NIH 3T3 line gain the capacity to produce neoplastically transformed foci when they are maintained at high density for more than 1 week and transferred in a standard assay for focus formation. This change in cell behavior has been variously attributed to an adaptive response to the cons...

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Bibliographic Details
Main Authors: Yao, A, Rubin, H
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC44472/
https://ncbi.nlm.nih.gov/pubmed/8052648
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