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Overexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmenting cellular apoptosis

Cisplatin is one of the most widely used anticancer agents, displaying activity against a wide variety of tumors. However, development of drug resistance presents a challenging barrier to successful cancer treatment by cisplatin. To understand the mechanism of cisplatin resistance, we investigated t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Barakat, Bassant M., Wang, Qi-En, Han, Chunhua, Milum, Keisha, Yin, De-Tao, Zhao, Qun, Wani, Gulzar, Arafa, El-Shaimaa A., El-Mahdy, Mohamed A., Wani, Altaf A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4180185/
https://ncbi.nlm.nih.gov/pubmed/20013802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25112
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