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Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Metabolic Disorders

After more than 20 years of development, lentiviral hematopoietic stem cell gene therapy has entered the stage of initial clinical implementation for immune deficiencies and storage disorders. This brief review summarizes the development and applications, focusing on the lysosomal enzyme deficiencie...

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Detalhes bibliográficos
Autor principal: Wagemaker, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179920/
https://ncbi.nlm.nih.gov/pubmed/25184354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.102
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