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Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Metabolic Disorders
After more than 20 years of development, lentiviral hematopoietic stem cell gene therapy has entered the stage of initial clinical implementation for immune deficiencies and storage disorders. This brief review summarizes the development and applications, focusing on the lysosomal enzyme deficiencie...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Mary Ann Liebert, Inc.
2014
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4179920/ https://ncbi.nlm.nih.gov/pubmed/25184354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2014.102 |
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