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From screen to target: insights and approaches for the development of anti-virulence compounds

A detailed understanding of host-pathogen interactions provides exciting opportunities to interfere with the infection process. Anti-virulence compounds aim to modulate or pacify pathogenesis by reducing expression of critical virulence determinants. In particular, prevention of attachment by inhibi...

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Hlavní autoři: Beckham, Katherine S. H., Roe, Andrew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179734/
https://ncbi.nlm.nih.gov/pubmed/25325019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2014.00139
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