Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds

A class of anti-virulence compounds, the salicylidene acylhydrazides, has been widely reported to block the function of the type three secretion system of several Gram-negative pathogens by a previously unknown mechanism. In this work we provide the first identification of bacterial proteins that ar...

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Bibliografiske detaljer
Main Authors: Wang, Dai, Zetterström, Caroline E., Gabrielsen, Mads, Beckham, Katherine S. H., Tree, Jai J., Macdonald, Sarah E., Byron, Olwyn, Mitchell, Tim J., Gally, David L., Herzyk, Pawel, Mahajan, Arvind, Uvell, Hanna, Burchmore, Richard, Smith, Brian O., Elofsson, Mikael, Roe, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191033/
https://ncbi.nlm.nih.gov/pubmed/21724850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233858
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