CT-2576, an inhibitor of phospholipid signaling, suppresses constitutive and induced expression of human immunodeficiency virus.

Viruses such as human immunodeficiency virus (HIV) require cellular activation for expression. Cellular activation in lymphoid cells is associated with augmented accumulation of certain phosphatidic acid (PA) species derived from the hydrolysis of glycan phosphatidylinositol (GPI). This suggests tha...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Leung, D W, Peterson, P K, Weeks, R, Gekker, G, Chao, C C, Kaplan, A H, Balantac, N, Tompkins, C, Underiner, G E, Bursten, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41797/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7761405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.11.4813
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