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Functional Annotation of Putative Regulatory Elements at Cancer Susceptibility Loci

Most cancer-associated genetic variants identified from genome-wide association studies (GWAS) do not obviously change protein structure, leading to the hypothesis that the associations are attributable to regulatory polymorphisms. Translating genetic associations into mechanistic insights can be fa...

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Detalhes bibliográficos
Main Authors: Rosse, Stephanie A, Auer, Paul L, Carlson, Christopher S
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4179605/
https://ncbi.nlm.nih.gov/pubmed/25288875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CIN.S13789
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